Sioux Falls, South Dakota, the state's largest city and the seat of Minnehaha County. It is located at a falls on the Big Sioux River in southeastern South Dakota, near the Iowa and Minnesota boundaries. Sioux Falls is the commercial and industrial center of the state, serving a large livestock- and grain-producing region. Meatpacking and other food processing are the primary industries. The city is also the headquarters for a number of credit-card companies. It is served by rail, air, and Interstate highways. The University of Sioux Falls and Augustana College are here.

Sioux Falls was founded in 1856 but was abandoned during an Indian uprising in 1862. In 1865 Fort Dakota was established there, and the town was resettled around it.

Population: 123,975.